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時間:2022-08-15 來源:本站 點擊:258次

Pfizer says COVID******

Pfizer said on Friday that a clinical trial of its pill to treat COVID-19 had shown it is highly effective, hailing it as a big step toward ending the pandemic.。

A simple pill to treat the coronavirus at home has been sought since the start of the global health crisis. So far all treatments have been either intravenous or vaccine shots.。

Pfizer's is the second anti-COVID pill after that of Merck, which is actually an influenza medicine rebranded to fight the coronavirus. Pfizer's has been created specifically to fight COVID-19.。

The Pfizer drug called Paxlovid achieved an 89 percent reduction in risk of hospitalization or death among adult patients with COVID-19 who are at high risk of progressing to severe illness, the US company said.。

The results from the middle-to-late stage clinical trial were so strong that Pfizer will stop recruiting new people for the trial, it said.。

Pfizer will submit the data to the Food and Drug Administration as soon as possible as part of its "rolling submission" for Emergency Use Authorization.。

"Today's news is a real game-changer in the global efforts to halt the devastation of this pandemic," said Pfizer CEO Albert Bourla.。

"These data suggest that our oral antiviral candidate, if approved or authorized by regulatory authorities, has the potential to save patients' lives, reduce the severity of COVID-19 infections, and eliminate up to nine out of 10 hospitalizations," he added.。

Bourla told CNN he hopes the company can submit its authorization request before the Thanksgiving holiday, which this year falls on November 25.。

President Joe Biden said in remarks at the White House that the government has already secured millions of doses of the new medication.。

He said the pill "would be another tool in our toolbox to protect people from the worst outcomes of COVID-19."

The main analysis of the Pfizer pill data looked at numbers from 1,219 adults in North and South America, Europe, Africa and Asia.。

In the days immediately after symptoms appeared, some of them were given the experimental drug and others got a placebo – for five days, every 12 hours.。

Ten people who took the placebo died, while among those who got the Pfizer medication, none did.。

The search for a pill。

Several companies are working on so-called oral antivirals, which would mimic what the drug Tamiflu does for influenza and prevent the disease from progressing to severe.。

Britain on Thursday became the first country to approve an anti-COVID pill, as it greenlit the use of Merck's antiviral drug called molnupiravir to treat patients suffering from mild to moderate coronavirus.。

Pfizer's product is known as a "protease inhibitor" and has been shown in lab testing to jam up the virus' replication machinery.。

If it works in real life, it will likely only be effective at the early stages of infection.。

By the time COVID-19 progresses to severe disease, the virus has largely stopped replicating and patients suffer from an overactive immune response.。

Until now, COVID-19 therapeutics such as monoclonal antibodies and Gilead's remdesivir – authorized for use in the EU under the name Veklury – have been administered intravenously.。

Merck's molnupiravir was initially developed as an inhibitor of influenza and respiratory syncytial virus – two other important acute respiratory infections – by a team at Emory University in Atlanta, Georgia.。

Britain, which has been one of the countries hardest hit by the pandemic, announced on October 20 that it had ordered 480,000 doses of molnupiravir.。

Pfizer is carrying out two other clinical trials with its pill: among people who are not at risk of progressing to severe COVID-19, and among people close to someone with COVID-19 to see if it protects them against the illness.。

Besides Pfizer and Merck, the Swiss pharma giant Roche is also working on a COVID pill.。

西安市公安局再通报6起涉疫违法案件 共7人被治安拘留******

  华商网讯 最近,西安公安部门依法惩治涉疫非法活动,依法查处了一批涉疫违反规定案子。现通告如下所示:










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Velez beat Boca to rise to third in Argentina's top flight******

BUENOS AIRES, Oct. 24 (Xinhua) -- Federico Mancuello and Cristian Tarragona scored either side of half-time as Velez Sarsfield clinched a 2-0 home win over Boca Juniors in Argentina's Primera Division on Sunday.

Mancuello opened the scoring in the 39th minute by firing a shot into the top-right corner and Tarragona put the result beyond doubt in second-half stoppage time with a low finish following a counterattack.

The result at El Fortin saw Velez displace Boca in third place in the 26-team standings.

Meanwhile, Jhonatan Candia struck an 85th-minute winner as Huracan prevailed 2-1 at home to San Lorenzo.

Franco Cristaldo gave the hosts the lead just after the hour mark before Franco Di Santo equalized in the 76th minute.

The result lifted Huracan to eighth place while San Lorenzo, who have now lost four consecutive matches and dropped to 21st.

In other Primera Division fixtures on Sunday, Colon won 2-1 at home to Estudiantes, and Godoy Cruz defeated Banfield 2-1 in Mendoza. Enditem

Chernobyl nuclear plant disconnected from power grid as Russian, Ukrainian FMs to meet in Turkey******


A safe confinement covering the fourth block of Chernobyl Nuclear power plant in Chernobyl, Ukraine, on April 15, 2021.

The Ukrainian state-run energy company Ukrenergo said Wednesday that the Chernobyl nuclear power plant in northern Ukraine has been disconnected from the power grid.

"The nuclear power plant in Chernobyl was fully disconnected from the power grid. The nuclear station has no power supply," Ukrenergo said in a statement on Telegram.

Military actions in the area are in progress so there is no possibility to restore the power lines, it said.

Ukrainian Foreign Minister Dmytro Kuleba on Twitter called on the international community to press an urgent demand that Russia cease-fire and allow repair units to restore the power supply to the nuclear power plant.

"Reserve diesel generators have a 48-hour capacity to power the Chernobyl NPP (Nuclear Power Plant). After that, cooling systems of the storage facility for spent nuclear fuel will stop, making radiation leaks imminent," Kuleba tweeted.

Russian Deputy Defense Minister Nikolai Pankov said on Wednesday that Ukraine's "nationalists" committed "an extremely dangerous provocation" by attacking the substation and power lines that feed the Chernobyl nuclear power plant.

Russian specialists have taken prompt measures to switch to backup diesel generators, he said at a briefing.

On Tuesday, the Vienna-based International Atomic Energy Agency said that remote data transmission from the safeguards control systems installed at the Chernobyl plant has been lost.

However, the United Nations nuclear watchdog denied any critical safety risk after receiving the Ukrainian report about the loss of power at the Chernobyl nuclear power plant on Wednesday.

"Heat load of spent fuel storage pool and volume of cooling water at Chernobyl Nuclear Power Plant sufficient for effective heat removal without need for electrical supply," the IAEA said in a statement posted on Twitter.

The Chernobyl nuclear plant, some 110 km north of Kiev, suffered one of the worst nuclear accidents in human history on April 26, 1986.

On February 24, Mykhailo Podoliak, adviser to the Head of the President's Office of Ukraine, said Russian forces have seized the Chernobyl nuclear power plant.

Russian and Ukrainian foreign ministers are expected to meet in Turkey's southern province of Antalya on Thursday on the sidelines of the Antalya Diplomatic Forum, according to Turkish Foreign Minister Mevlut Cavusoglu.

The meeting is set to be held in a tripartite format, as part of Turkey's "intense effort" to bring both sides together.

Before the planned meeting, Russian President Vladimir Putin and German Chancellor Olaf Scholz held a phone conversation on Wednesday to explore political and diplomatic efforts toward a possible settlement of the Ukraine crisis.

Putin and Scholz discussed the results of the third round of negotiations between the Russian and Ukrainian delegations, the Kremlin said in a statement.

The leaders also paid special attention to humanitarian issues arising from the current situation, it said, adding that Putin briefed Scholz about measures taken to organize humanitarian corridors for the evacuation of civilians.

Also on Wednesday, the Russian Foreign Ministry called on Washington to explain to the international community the purpose of the US-funded biological laboratories in Ukraine.

"We remember for how many years and with what bloody results the United States searched for various types of chemical, biological, bacteriological weapons and so on all over the world, actually occupying lands and killing people," the ministry's spokesperson Maria Zakharova told a briefing.

She said that Kiev has recently begun erasing traces of these biological programs.

"We received documentation from Ukrainian employees at the biological laboratories on the urgent destruction of especially dangerous pathogens, plague, anthrax, cholera and other deadly diseases on February 24," she said.


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