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時間:2022-08-15 來源:本站 點擊:258次
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Pfizer says COVID******

Pfizer said on Friday that a clinical trial of its pill to treat COVID-19 had shown it is highly effective, hailing it as a big step toward ending the pandemic.。

A simple pill to treat the coronavirus at home has been sought since the start of the global health crisis. So far all treatments have been either intravenous or vaccine shots.。

Pfizer's is the second anti-COVID pill after that of Merck, which is actually an influenza medicine rebranded to fight the coronavirus. Pfizer's has been created specifically to fight COVID-19.。

The Pfizer drug called Paxlovid achieved an 89 percent reduction in risk of hospitalization or death among adult patients with COVID-19 who are at high risk of progressing to severe illness, the US company said.。

The results from the middle-to-late stage clinical trial were so strong that Pfizer will stop recruiting new people for the trial, it said.。

Pfizer will submit the data to the Food and Drug Administration as soon as possible as part of its "rolling submission" for Emergency Use Authorization.。

"Today's news is a real game-changer in the global efforts to halt the devastation of this pandemic," said Pfizer CEO Albert Bourla.。

"These data suggest that our oral antiviral candidate, if approved or authorized by regulatory authorities, has the potential to save patients' lives, reduce the severity of COVID-19 infections, and eliminate up to nine out of 10 hospitalizations," he added.。

Bourla told CNN he hopes the company can submit its authorization request before the Thanksgiving holiday, which this year falls on November 25.。

President Joe Biden said in remarks at the White House that the government has already secured millions of doses of the new medication.。

He said the pill "would be another tool in our toolbox to protect people from the worst outcomes of COVID-19."

The main analysis of the Pfizer pill data looked at numbers from 1,219 adults in North and South America, Europe, Africa and Asia.。

In the days immediately after symptoms appeared, some of them were given the experimental drug and others got a placebo – for five days, every 12 hours.。

Ten people who took the placebo died, while among those who got the Pfizer medication, none did.。

The search for a pill。

Several companies are working on so-called oral antivirals, which would mimic what the drug Tamiflu does for influenza and prevent the disease from progressing to severe.。

Britain on Thursday became the first country to approve an anti-COVID pill, as it greenlit the use of Merck's antiviral drug called molnupiravir to treat patients suffering from mild to moderate coronavirus.。

Pfizer's product is known as a "protease inhibitor" and has been shown in lab testing to jam up the virus' replication machinery.。

If it works in real life, it will likely only be effective at the early stages of infection.。

By the time COVID-19 progresses to severe disease, the virus has largely stopped replicating and patients suffer from an overactive immune response.。

Until now, COVID-19 therapeutics such as monoclonal antibodies and Gilead's remdesivir – authorized for use in the EU under the name Veklury – have been administered intravenously.。

Merck's molnupiravir was initially developed as an inhibitor of influenza and respiratory syncytial virus – two other important acute respiratory infections – by a team at Emory University in Atlanta, Georgia.。

Britain, which has been one of the countries hardest hit by the pandemic, announced on October 20 that it had ordered 480,000 doses of molnupiravir.。

Pfizer is carrying out two other clinical trials with its pill: among people who are not at risk of progressing to severe COVID-19, and among people close to someone with COVID-19 to see if it protects them against the illness.。

Besides Pfizer and Merck, the Swiss pharma giant Roche is also working on a COVID pill.。

西安市公安局再通报6起涉疫违法案件 共7人被治安拘留******

  华商网讯 最近,西安公安部门依法惩治涉疫非法活动,依法查处了一批涉疫违反规定案子。现通告如下所示:

  一、白某拒不履行紧急状况下的决策案。12月27日,白某违背“出不来户、不集聚”疫防监管规定,欲离去住宅小区时,工作员对它进行劝说,白某谩骂工作员并毁坏防疫工作标识牌。公安机关莲湖大队根据《中华人民共和国治安管理处罚法》第四十九条、第五十条之要求,给予白某治安拘留十三日的惩罚。

  二、张某、许某扰乱公共场合纪律案。12月23日,张某和村民在排号等待抗体检测时,对管理人员分配不满意,抓扯工作员,扰乱抗体检测纪律。公安机关西安临潼大队根据《中华人民共和国治安管理处罚法》第二十三条之要求,各自给予张某、许某治安拘留十日的惩罚。

  三、柯某拒不履行紧急状况下的决策案。12月23日,柯某违背疫情防控工作标准,毁坏住宅小区停车库出入口智能道闸后,强制驾驶驶出。西咸新区派出所沣东新城大队根据《中华人民共和国治安管理处罚法》第五十条之要求,给予柯某治安拘留十日的惩罚。

  四、王某寻衅滋事罪案。12月24日,王某在蓝田县蓝关街道办事处疫情防控点不遵从工作员管理方法,摔砸疫防器材,影响防疫工作进行。蓝田县派出所根据《中华人民共和国治安管理处罚法》第二十六条之要求,给予王某治安拘留十二日的惩罚。

  五、罗某编造客观事实扰乱公共秩序案。12月25日,罗某在网络上散布“某省三生三世凉凉了,大街上去世了很多人”等谣传,扰乱媒体传播纪律和公共秩序。公安机关渭城大队根据《中华人民共和国治安管理处罚法》第二十五条之要求,给予罗某治安拘留十日的惩罚。

  六、吴某编造客观事实扰乱公共秩序案。12月25日,吴某编造“某镇封控不许出村,村霸结伙小混混持械砍医务人员,被警察打枪枪杀”等虚假信息内容,在互联网上公布,扰乱媒体传播纪律和公共秩序。公安机关碑林大队根据《中华人民共和国治安管理处罚法》第二十五条之要求,给予吴某治安拘留七日的惩罚。

  公安部门提示广大群众人民群众:维护保养疫情防控工作中纪律从我做起。期待广大群众人民群众严格执行《有关加强疫情防控期内社会发展面监管的通知》规定,积极执行疫防义务和社会发展责任,紧密配合进行防疫工作。公安部门积极主动确保人民群众就诊等应急必需的交通出行主题活动,坚持不懈以民为本,进一步协助人民群众化解因难;对拒不执行疫情防控对策,扰乱公共秩序的,依规严厉查处。



来源于:华商网。

编写:田媛。

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Velez beat Boca to rise to third in Argentina's top flight******

BUENOS AIRES, Oct. 24 (Xinhua) -- Federico Mancuello and Cristian Tarragona scored either side of half-time as Velez Sarsfield clinched a 2-0 home win over Boca Juniors in Argentina's Primera Division on Sunday.

Mancuello opened the scoring in the 39th minute by firing a shot into the top-right corner and Tarragona put the result beyond doubt in second-half stoppage time with a low finish following a counterattack.

The result at El Fortin saw Velez displace Boca in third place in the 26-team standings.

Meanwhile, Jhonatan Candia struck an 85th-minute winner as Huracan prevailed 2-1 at home to San Lorenzo.

Franco Cristaldo gave the hosts the lead just after the hour mark before Franco Di Santo equalized in the 76th minute.

The result lifted Huracan to eighth place while San Lorenzo, who have now lost four consecutive matches and dropped to 21st.

In other Primera Division fixtures on Sunday, Colon won 2-1 at home to Estudiantes, and Godoy Cruz defeated Banfield 2-1 in Mendoza. Enditem

Chernobyl nuclear plant disconnected from power grid as Russian, Ukrainian FMs to meet in Turkey******

Imaginechina

A safe confinement covering the fourth block of Chernobyl Nuclear power plant in Chernobyl, Ukraine, on April 15, 2021.

The Ukrainian state-run energy company Ukrenergo said Wednesday that the Chernobyl nuclear power plant in northern Ukraine has been disconnected from the power grid.

"The nuclear power plant in Chernobyl was fully disconnected from the power grid. The nuclear station has no power supply," Ukrenergo said in a statement on Telegram.

Military actions in the area are in progress so there is no possibility to restore the power lines, it said.

Ukrainian Foreign Minister Dmytro Kuleba on Twitter called on the international community to press an urgent demand that Russia cease-fire and allow repair units to restore the power supply to the nuclear power plant.

"Reserve diesel generators have a 48-hour capacity to power the Chernobyl NPP (Nuclear Power Plant). After that, cooling systems of the storage facility for spent nuclear fuel will stop, making radiation leaks imminent," Kuleba tweeted.

Russian Deputy Defense Minister Nikolai Pankov said on Wednesday that Ukraine's "nationalists" committed "an extremely dangerous provocation" by attacking the substation and power lines that feed the Chernobyl nuclear power plant.

Russian specialists have taken prompt measures to switch to backup diesel generators, he said at a briefing.

On Tuesday, the Vienna-based International Atomic Energy Agency said that remote data transmission from the safeguards control systems installed at the Chernobyl plant has been lost.

However, the United Nations nuclear watchdog denied any critical safety risk after receiving the Ukrainian report about the loss of power at the Chernobyl nuclear power plant on Wednesday.

"Heat load of spent fuel storage pool and volume of cooling water at Chernobyl Nuclear Power Plant sufficient for effective heat removal without need for electrical supply," the IAEA said in a statement posted on Twitter.

The Chernobyl nuclear plant, some 110 km north of Kiev, suffered one of the worst nuclear accidents in human history on April 26, 1986.

On February 24, Mykhailo Podoliak, adviser to the Head of the President's Office of Ukraine, said Russian forces have seized the Chernobyl nuclear power plant.

Russian and Ukrainian foreign ministers are expected to meet in Turkey's southern province of Antalya on Thursday on the sidelines of the Antalya Diplomatic Forum, according to Turkish Foreign Minister Mevlut Cavusoglu.

The meeting is set to be held in a tripartite format, as part of Turkey's "intense effort" to bring both sides together.

Before the planned meeting, Russian President Vladimir Putin and German Chancellor Olaf Scholz held a phone conversation on Wednesday to explore political and diplomatic efforts toward a possible settlement of the Ukraine crisis.

Putin and Scholz discussed the results of the third round of negotiations between the Russian and Ukrainian delegations, the Kremlin said in a statement.

The leaders also paid special attention to humanitarian issues arising from the current situation, it said, adding that Putin briefed Scholz about measures taken to organize humanitarian corridors for the evacuation of civilians.

Also on Wednesday, the Russian Foreign Ministry called on Washington to explain to the international community the purpose of the US-funded biological laboratories in Ukraine.

"We remember for how many years and with what bloody results the United States searched for various types of chemical, biological, bacteriological weapons and so on all over the world, actually occupying lands and killing people," the ministry's spokesperson Maria Zakharova told a briefing.

She said that Kiev has recently begun erasing traces of these biological programs.

"We received documentation from Ukrainian employees at the biological laboratories on the urgent destruction of especially dangerous pathogens, plague, anthrax, cholera and other deadly diseases on February 24," she said.

爱,是一个个无可替代日子的积累——军恋不易,唯你美好

1.基辛格:美在一定程度上制造问题 与中俄处于战争边缘

2.庆祝回归25周年 香港街头闪耀中国红

3.8个好友抱团搬到福建山村 住土屋过低物欲生活

4.媒体评论:“探店”亟待纳入广告监管范畴

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